New version: (Click Here)

Prepare for your medical exam, USMLE, MCCEE with a FREE MCQs and clinical cases! ECG, CXR and all types of free medical MCQs with answers, good luck! Medical MCQs from students to students.

A 45-year-old female treated for ovarian cancer develops difficulty hearing. Which of the following agents most likely caused these findings?

a. Paclitaxel
b. Doxorubicin
c. Bleomycin
d. 5-FU
e. Cisplatin


in Otolaryngology by

1 Answer

0 votes
Best answer
The answer is e. (Hardman, pp 1269–1271.) Cisplatin causes acoustic nerve damage. Paclitaxel causes peripheral neuritis. Dose- dependent pneumonitis and fibrosis are caused by bleomycin. Doxorubicin causes cardiac toxicity, which may lead to congestive heart failure. 5-Fluorouracil causes myelosuppression, stomatitis, and oral and gastrointestinal ulcerations.