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Which of the following hormones is used in the treatment of depression?

a. Progesterone
b. Cortisol
c. ACTH
d. Levothyroxine
e. Prolactin
in Psychiatry by

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D. Levothyroxine

 (Sadock, 7/e, pp 2478–2482.)
The connection between thyroid function and mood disorders has been known for more than a century, since nineteenth-century physicians noticed that hypothyroidism was accompanied by depression. All the hormones of the hypothalamic-pituitary-thyroid axis have been used in the treatment of depression, alone or in combination with other agents, although the most commonly used are liothyronine and levothyroxine.
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