A newborn child is brought to the attention of the pediatrician since he has still failed to pass meconium in the first 72 hours and that there is no stool in the diaper. On examination, the infant has a notably distended abdomen, and there is good anal tone. A pilocarpine sweat test is within normal limits. An ultrasound of abdomen is within normal limits. A barium enema shows a large dilated segment of transverse colon.
What is most likely cause for this infant's constipation?
a. Defective CFTR transporter
b. Duodenal atresia
c. Lack of ganglion cells in distal colon
d. Telescoping of bowel segment
e. Hypertrophic pylorus